通过实例介绍污染物-皮肤接触暴露的量化方法.选择了多环芳烃污染较严重的天津市,计算了该地区人群通过2种主要皮肤接触途径(皮肤-降尘接触和皮肤-洗浴水接触)对区域环境中16种PAH化合物(PAH16)的皮肤接触暴露与健康风险.儿童、青少年和成人三个亚群对PAH16的日均皮肤接触暴露量分别为3.41×10^-2、2.68×10^-2、1.95×10^-2μg·kg^-1·d^-1.终生加权暴露量为2.20×10^-2μg·kg^-1·d^-1.不确定性分析的结果表明,至少50%人群对PAH16暴露量在2.00×10^-2—4.00×10^-2μg·kg^-1·d^-1范围内,暴露量极高和极低的人都很少.在16种化合物中,皮肤接触暴露优势化合物是Phe,Fla,Pyr,Bap和Baa.皮肤途径终生加权暴露对总暴露量的贡献很低(1.06%),换算为BaP等效浓度(BaPeq)后则增加到6.00%.人群由于PAH16皮肤接触暴露所导致的平均致癌风险为8.1×10^-7a^-1,并未超出最大可接受风险1×10^-5a^-1.
The aim of the study was to introduce the method of calculating PAH dermal exposure.A PAHs heavily polluted city,Tianjin,was selected as an example to give quantitative result of dermal exposure and health risk of PAHs in the regional environment.The dermal exposure model recommended by USEPA was applied to estimate the exposure of the priority 16 PAHs(PAH16) through two main routes(skin-dust contact and skin-bath water contact).It was found that the dermal exposure of the children,teenagers and adults was 3.41×10^-2,2.68×10^-2 and 1.95×10^-2 μg·kg^-1·d^-1,respectively.Therefore the age-weighted lifetime dermal exposure was 2.20×10^-2 μg·kg^-1·d^-1.Uncertainty analysis showed that at least 50% of population exposure to PAH16 ranged from 2.00×10^-2 to 4.00×10^-2 μg·kg^-1·d^-1 with few extremely high and low values.The major compounds of the skin route exposure were Phe,Fla,Pyr,Bap plus Baa.After BaP equivalent concentration(BaPeq) being converted,the contribution of dermal exposure to the total exposure increased from 1.06% to 6.00%.Accordingly,the average value of the carcinogenic risk caused by PAH16 dermal exposure was 8.1×10^-7 a^-1,which was below the maximum acceptable risk of 1×10^-5 a^-1.