中文摘要：

为预防间歇式反应器热失控风险,以恒温间歇式丙酸异丙酯合成反应为原型,利用反应量热仪（RC1e）获得不同冷却温度下反应放热特性及热动力学参数,并对计算流体力学（CFD）软件Fluent模拟结果进行试验验证。基于经验证的CFD耦合模型,对反应过程中搅拌和冷却失控情景进行模拟分析,分别从搅拌转速、冷却温度以及冷却流速失控3方面,研究失控情景对反应温升的影响。结果表明：反应温升对不同失控情景存在参数敏感性,其中冷却流速对反应温升影响较大,较低的入口冷却流速直接促使局部换热死区的形成,使失控时间相对标准工况提前近1/5,温度提高近22℃;以反应失控判据Chaos准则为警报标准,确定反应器最佳温度探测器应安装在反应液系内部远离冷却入口且靠近液面1/3处及以上的位置。

英文摘要：

For the sake of preventing stirred batch reactor thermal runaway experiments were carried on the synthesis reaction of isopropyl propionate.Reaction calorimeters （RC1e） were used to analyze the thermal behavior and kinetics of the reaction under different initial temperature conditions.The CFD simulation results got by Fluent software were validated by experiment.The simulation results were basically in agreement with the experimental results.Based on the obtained kinetic parameters,influences of temperature control system runaway,cooling system runaway and stirring system runway on reaction temperature risk were analyzed.The results show that the experimental temperature rising has a highly parameter sensitivity with working condition,the cooling velocity has a great influence on the reaction temperature,that the lower inlet cooling velocity directly causes local heat transfer dead zones to form,which makes thermal runaway time shorten by nearly 20%,compared with normal condition,and the temperature increase by nearly 22℃,and that the position where the reasonable temperature probe is set up should be at the top of the reactor,about 1/3 of the radical distance for the reactor according to the Chaos theory.