中文摘要：

到在急性冠的症候群(交流) 以后的病人的第二等的预防药(ATM ) 的低坚持与差的临床的结果被联系。然而，文学在对与交流在中国病人与穷人联系的 ATM 和风险的评价以后提供有限数据。在当前的工作， ATM 在 Tongji 与交流在连续地招募的病人被估计从 2013 年 11 月 5 日的医院到 2014 年 12 月 31 日。2126 个病人的一个总数在低坚持下面被分类(盖住的天(PDC ) 分配 C <50%) 并且高坚持(PDC >50%) 在分泌物以后基于他们的表演组织。所有病人被跟随在上面在第一，第 6，和第 12 月当记录 ATM 和主要不利心脏的事件(向) 时，排出。Bivariate 逻辑回归被用来识别与 ATM 联系的因素。考克斯回归被用来在分泌物以后在一年以内分析在 ATM 和向之间的协会。结果证明冠的动脉独自绕过 grafting (CABG ) 到 P2Y12 对手的高坚持的有的显著地更低的比例(83.0% 对 90.7% ， P < 0.01 ) 比仅仅与经皮的冠的干预(一种总线标准) 对待的病人。而且在经历一种总线标准的病人，到 P2Y12 对手的高坚持减少了向的风险(危险比率 = 0.172， 95% 信心间隔：0.039-0.763；P = 0.021 ) 。在结论，对待一种总线标准的病人是对比对待 CABG 的病人仍然是支持者到药敏感的更多。到 P2Y12 对手的高坚持与向的更低的风险被联系。

英文摘要：

Low adherence to secondary prevention medications （ATM） of patients after acute coronary syndrome （ACS） is associated with poor clinical outcomes. However, literature provides limited data on assessment of ATM and risks associated with poor in Chinese patients with ACS. In the current work, ATM was assessed in consecutively recruited patients with ACS in Tongji Hospital from November 5, 2013 to December 31, 2014. A total of 2126 patients were classified under low adherence （proportion of days covered （PDC）〈 50%） and high adherence （PDC〉50%） groups based on their performance after discharge. All patients were followed up at the 1st, 6th, and 12th month of discharge while recording ATM and major adverse cardiac events （MACE）. Bivariate logistic regression was used to identify the factors associated with ATM. Cox regression was used to analyze the association between ATM and MACE within one year after discharge. Results showed that coronary artery bypass grafting （CABG） alone had significantly lower proportion of high adherence to P2Y12 antagonists （83.0% vs. 90.7%, P 〈 0.01） than patients treated with percutaneous coronary intervention （PCI） only. Moreover, in patients undergoing PCI, high adherence to P2Y12 antagonists decreased the risk of MACE （hazard ratio = 0.172, 95% confidence interval： 0.039-0.763; P= 0.021）. In conclusion, PCI-treated patients are more prone to remaining adherent to medications than CABG-treated patients. High adherence to P2Y12 antagonists was associated with lower risk of MACE.