中文摘要：

人类基因组90％可以发生转录，但98％的转录产物为不具有蛋白编码能力的非编码 RNA（noncoding RNA， ncRNA）。长链非编码RNA（long noncoding RNA， lncRNA）是指转录本超过200 nt的非编码RNA，曾一度被认为是转录的“噪音”，不具有任何生物学功能。然而，近年报道lncRNA广泛参与成肌分化，可在RNA水平通过多种方式调控成肌分化进程，是成肌分化的重要调节因子。

英文摘要：

About 90% of the human genome can be transcribed, but only 2% of transcripts are translated into proteins-Long noncoding RNA （ lncRNA） is one kind of noncoding RNA which has〉200 nt transcripts and was once seen to be transcription “noise”, without any biological function-However, in recent years, it was reported that many lncRNAs widely participate in myo-genic differentiation-LncRNA can regulate myogenic differentiation in different patterns at the RNA level and may be an important regulatory factor in myogenic differentiation.