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中文摘要：
以羧甲基纤维素钠为交联剂，将羟丙基-β-环糊精固载在硅胶GF254板上，作为固定相制成层析薄板，成功用于拆分盐酸克伦特罗对映异构体。考察了展开剂对层析薄板分离效果的影响，发现展开剂中醇的种类和比例对拆分效果有很大的影响，含4个碳的醇类包括正丁醇、仲丁醇、叔丁醇可使盐酸克伦特罗得以拆分。确定了实验的最佳条件：V（乙腈）：V（叔丁醇）=50：50，展开时间约为12min。
英文摘要：
The resolution of clenbuterol hydrochloride enantiomers was achieved by thin-layer chromatography on silica gel GF254 plates impregnated with hydroxypropyl-β-cyclodextrin. The effect of stereoselective auxiliary （acetonitrile and alcohol） was investigated. From methanol to octanol, resolution of clenbuterol hydrechloride enantiomers could be attained by using alcohols of four carbon atoms such as butanol, 2-butanol or tert-butanol together with acetonitrile. The mechanism of resolution was investigated, the optimal conditions of resolution were determined as follows ： acetonitrile： tea-butanol = 50：50（v/v） under ambient temperature, being resolved for about 12 min.
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