中文摘要：

N-甲氧基-N-甲基酰胺,自从被发现后广泛称为Weinreb酰胺（WAs）,具有与一般酰胺不同的反应特性.它既可与有机锂或镁试剂反应作为一种优秀酰基化试剂,又可作为醛基等价体.由于其作为合成砌块在大量有机合成反应中被使用,综述了Weinreb酰胺的制备及其新合成应用.

英文摘要：

N-Methoxy-N-methylamides, now popularly called Weinreb amides （WAs） after their discovery, have surfaced as amides with a difference. This amide has served as an excellent acylating agent for organolithium or organomagnesium reagents and as an effective equivalent for an aldehyde group. These two aspects have been exploited exhaustively in many synthetic strategies. The growing synthetic utility and preparation of the Weinreb amides are reviewed.