中文摘要：

制备了以聚丙烯酸钠为基材的高分子水凝胶退热贴。退热贴的含水率为56％～60%。对钢板和人造革的剥离力分别为26．6g／cm和14．8g／cm，粘附力达到日本产退热贴的水平。动物试验证明自制退热贴对内毒素致家兔体温升高有退热作用，使用后2～2．5h的退热效果较明显，5h后，家兔体温基本恢复正常。初步临床实验也证明自制退热贴具有良好的退热效果，有效时间为4～6h。

英文摘要：

Cooling paste based on polyacrylate hydrogel was fabricated via radical polymerization. The water content of this cooling paste is 56%～60%. The dynamic module of the paste exhibited a viscoelasticity well as that of a commercial one made in Japan. The peeling strength from steel and artificial leather is 26.6 g/cm and 14.8 g/cm, respectively. Animal test indicates that our cooling paste based on polyacrylate hydrogel is effective in treatment of fever caused by endotoxin the rabbit temperature became normal in about 5 h after treatment. It was further tested with elementary clinical trial and the effective time was 4～6 h.