中文摘要：

杂环化合物在药物和农药领域具有多种优良的生物活性,其合成方法是目前药物和农药研究的热点领域之一.以绿色合成为主题,介绍了无溶剂杂环有机合成在产率高、选择性好、操作简便、成本低及环境友好等绿色化学方面的优点,综述了近四年无溶剂反应在杂环合成方面研究的最新进展.

英文摘要：

Heterocyclic compounds have shown many excellent biological activities in both area of medicine and pesticide.The synthetic method is one of the focused fields concerning pharmaceutical and pesticidal researches at present.With the theme of green synthesis,some advantadges of organic solvent-free heterocyclic synthesis in high yield,good selectivity,easy operation,low cost and environmental friendship were introduced.And the developments in the recent four years of solvent-free reaction in heterocyclic synthesis study have been reviewed.