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Onxy胶栓塞颈外动脉分支为主要供血海绵窦区动静脉瘘的临床研究
  • ISSN号:1001-2346
  • 期刊名称:《中华神经外科杂志》
  • 时间:0
  • 分类:R743.4[医药卫生—神经病学与精神病学;医药卫生—临床医学]
  • 作者机构:[1]陕西省榆林市第二医院神经外科, [2]首都医科大学北京市神经外科研究所首都医科大学附属北京天坛医院神经介入科,100050
  • 相关基金:北京市科技新星计划交叉学科合作课题(Z141107001814120),首都卫生发展科研专项(2014-3-2044),国家自然科学基金(81441038),北京自然科学基金(7142032)
中文摘要:

目的 探讨经动脉入路Onyx胶栓塞治疗颈外动脉分支为主要供血的海绵窦区硬脑膜动静脉瘘(CSDAVF)的可行性、并发症和疗效.方法 回顾性分析2005年8月至2014年10月收治的15例(其中北京天坛医院神经介入科13例,榆林市第二医院神经外科2例)Onyx胶栓塞治疗颈外动脉分支为主要供血的CSDAVF的临床资料和随访结果.结果 术后即刻造影提示12例完全栓塞,3例瘘口部分残留.术后眼部症状缓解14例,并发同侧面部麻木3例,面瘫1例,复视1例.随访3 - 24个月,造影结果提示13例完全治愈,1例造影提示复发行二次栓塞治疗,1例残留较前无变化.临床随访提示眼部症状均缓解,无出血,并发症状均缓解.结论 经颈外动脉分支入路微导管可到达瘘口的CSDAVF,Onyx胶栓塞治疗CSDAVF是可行的,是经静脉入路不能到位或者治疗失败后的替选方案.

英文摘要:

Objective To investigate the feasibility,complications and efficacy of main blood-supply cavernous sinus dural arteriovenous fistulas (CSDAVFs) for the embolization treatment of the branches of external carotid artery with Onyx via artery approach.Methods The clinical data and follow-up results of 15 patients (13 patients from the Neurointerventional Department of Beijing Tiantan Hospital and 2 patients from the Department of Neurosurgery,the Second Hospital of Yulin) treated with the main blood-supply CSDAVFs for the embolization treatment of the branches of external carotid artery with Onyx from August 2005 to october 2014 were analyzed retrospectively.Results Immediately after procedure,angiography revealed that 12 patients were embolized completely,3 had partially residual fistula.The postoperative ocular symptoms of 14 patients were relieved,3 complicated with ipsilateral facial numbness,one had facial paralysis,and one had diplopia.They were followed up for 3 to 24 months,angiographic findings revealed that 13 patients were cured completely,one had recurrence and received the second embolization,and the residue did not have any change in one case.The clinical follow-up showed that their ocular symptoms were all relieved,no hemorrhage was observed,and all the complications were relieved.Conclusions Microcatheter can reach CSDAVFs of fistula via the branches of external carotid artery approach.Onyx embolization of CSDAVFs is feasible.It is an alternative scheme which the microcatheter can not be in place via venous approach or after treatment failure.

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期刊信息
  • 《中华神经外科杂志》
  • 中国科技核心期刊
  • 主管单位:中国科协
  • 主办单位:中华医学会
  • 主编:
  • 地址:北京市崇文区天坛西里6号
  • 邮编:100050
  • 邮箱:cjns65113169@sian.com
  • 电话:010-65113169
  • 国际标准刊号:ISSN:1001-2346
  • 国内统一刊号:ISSN:11-2050/R
  • 邮发代号:18-56
  • 获奖情况:
  • 1997年中国科协优秀科技期刊二等奖,1995年中华医学会成立80周年银奖
  • 国内外数据库收录:
  • 日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),中国北大核心期刊(2000版)
  • 被引量:39789