相关基金:National Natural Science Foundation of China(81071906, 81172127, 81572969, 81402633); Technology and Development and Research Projects for Research Institutes, Ministry of Science and Technology(2014EG150134); Tianjin Science & Technology Pillar Program(14ZCZDSY00001); Natural Science Foundation of Tianjin(16JCQNJC13600); Peking Union Medical College Youth Innovation Fund(1581); IRM-CAMS Research Fund(1614)