中文摘要：

为寻找高活性的含杂环农药，由中间体5-烷基-1，3，4-噻二唑与对苯二甲酰基二异硫氰酸酯反应，合成6种新的含1，3，4-噻二唑环的对苯二甲酰基双硫脲化合物Ⅲa-f。通过元素分析、红外光谱、核磁共振氢谱对所合成的化合物进行结构表征。生物活性测试结果表明：所合成的目标化合物对受试菌种小麦赤霉病菌，水稻纹枯病菌、棉枯萎病菌和油菜菌核病菌均表现出一定的抑制活性，但对棉枯萎病菌的抑制活性均较差。其中化合物Ⅲa和Ⅲb分别对油菜菌核病菌和水稻纹枯病菌有较强的抑制活性，抑制率分别为40．4％和51．6％，Ⅲf抑菌活性较弱。

英文摘要：

In order to find high active pesticide containing heterocycle, six novel terephthaloyl bisthioureas（Ⅲa-f） containing 1, 3, 4-thiodiazole were synthesized by the reaction of 2-amino-5-alkyl-1, 3, 4-thiodiazoles with terephthaloyl diisothiocyanate. Their structures were confirmed by elemental analysis, IR spectra and ^1HNMR. The preliminary biological activity tests show that the title compounds have some fungicidal activities using Gibberella zeae, Rhizoctonia solani, Fusarium oxysporium and Sclerotinia sclerotiorum as the target fungus, but all of them have poor fungicidal activity to Fusarium oxysporium. The compounds Ⅲa and Ⅲb have good fungicidal activity to Sclerotinia sclerotiorum and Rhizoctonia solanL and their inhibition ratios are 40.4% and 51.6%, respectively.