中文摘要：

上皮-间质转化是上皮细胞向间质细胞转变的过程,其与肿瘤侵袭、转移等恶性行为密切相关,近年受到广泛关注。前列腺癌是老年男性发病率较高的肿瘤,上皮-间质转化在前列腺癌转移过程中具有重要作用。本文对前列腺癌上皮-间质转化研究进展作一综述,为深入了解前列腺癌转移机制及防治提供思路。

英文摘要：

Epithelial-mesenchymal transition（EMT） is a process in which the epithelial cells transform into mesenchymal cells. As it closely associates with the malignant behavior of tumor such as invasion and metastasis, it attracts widespread attention in recent years. Prostate cancer is a threat for elder men, and EMT plays an important role in prostate cancer metastasis. In this paper, the research progress of EMT in prostate cancer will be reviewed to expand thoughts of the mechanism, prevention and treatment of prostate cancer metastasis.