东篱科研大数据发现系统（DRDS）

位置：成果数据库 > 期刊 > 期刊详情页

丙泊酚的不同药物配伍在无痛人流女性中的麻醉效果研究

ISSN号：1672-1993
期刊名称：《中国性科学》
时间：0
分类：R169.42[医药卫生—公共卫生与预防医学]
作者机构：[1]杭州市妇产科医院麻醉科,杭州310008, [2]浙江中医药大学附属第三医院妇产科,杭州310008, [3]浙江大学医学院附属邵逸夫医院麻醉科,杭州310005
相关基金：浙江省医学会临床科研基金项目（2011ZYC-A01）

关键词：丙泊酚, 无痛人流, 芬太尼, 舒芬太尼, 瑞芬太尼, Propofol, Painless induced abortion, Fentanyl, Sufentanil, Remifentanil

中文摘要：

目的：探讨丙泊酚配伍不同阿片类受体激动剂在无痛人流女性中的麻醉效果的研究。方法：随机选择2013年1月至2015年6月于我院自愿进行无痛人流方式终止妊娠的早孕妇女240例,随机分为丙泊酚搭配芬太尼（A组）、丙泊酚搭配瑞芬太尼（B组）和丙泊酚搭配舒芬太尼（C组）,每组80例。记录患者手术后的苏醒时间、离院时间、疼痛等级以及RAAS评分和BCS评分,并记录患者满意度。结果：三种配伍患者的苏醒时间上没有显著差异,但是丙泊酚配伍舒芬太尼的离院时间以及疼痛评分上显著优于配伍瑞芬太尼和芬太尼（P〈0.05）。RAAS评分和BCS评分均表明,丙泊酚配伍舒芬太尼在RAAS和BCS评分上显著优于配伍芬太尼和舒芬太尼（P〈0.05）;同时与丙泊酚配伍芬太尼相比,配伍瑞芬太尼的患者RAAS和BCS评分也有显著改善（P〈0.05）。满意度结果也显示,配伍舒芬太尼的患者满意度显著优于其他两种配伍处方。结论：3种配伍均可安全有效的用于无痛人流,但是考虑到舒适性和经济性,丙泊酚配伍舒芬太尼更为适合用于无痛人流,值得临床借鉴使用。

英文摘要：

Objectives： To investigate the anesthetic effect of propofol and different opioid receptor agonist in painless induced abortion. Methods： 240 early pregnancy women came to our hospital from January 2013 to June2015 for painless induced abortion were selected and randomly divided into propofol with fentanyl（ group A）,propofol with remifentanil（ group B） and propofol with sufentanil（ group C）,80 cases in each group. The recovery time after surgery,hospital stay,pain levels and RAAS and BCS ratings as well as patient＇s satisfaction were recorded. Results： There was no significant difference in recovery time among the three groups,but the hospital stay and pain scores of group A was significantly superior to group B and C（ P〈0. 05）. The RAAS and BCS score of group A was significantly superior to group B and C（ P〈0. 05）; and that of group B was better than group C（ P〈 0. 05）. Patients in group A were also more satisfied than group B and C. Conclusion： The three combinations are all safe and effective for painless induced abortion,but considering the comfort and economic efficiency,joint use of propofol and sufentanil is more suitable for painless induced abortion,which is worthy of clinical application.