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7种动物血清抗-HEV抗体检测
  • 期刊名称:中国人畜共患病学报,2007,23(11):1105-1106
  • 时间:0
  • 分类:R373.2[医药卫生—病原生物学;医药卫生—基础医学]
  • 作者机构:[1]北京大学医学部病原生物学系,北京100083, [2]新疆巴音郭楞蒙古自治州且末县医院, [3]且末县卫生防疫站, [4]和田地区疾病控制中心
  • 相关基金:国家自然科学基金资助项目(30570063),国家863项目(2006AA02Z453)
  • 相关项目:戊型肝炎病毒基因1型动物宿主及其致病性研究
中文摘要:

目的了解猕猴、鼠、旱獭、鸽子、鸡、鱼、蟾蜍血清中抗-HEV抗体流行情况。方法应用双抗原夹心酶联免疫法检测猕猴、鼠、旱獭、鸽子、鸡、鱼和蟾蜍血清中抗-HEV抗体。结果总抗-HEV抗体阳性率为14.41%(113/784)。7种动物中猕猴血清抗-HEV抗体阳性率为7.26%(9/124);鼠和旱獭抗-HEV抗体阳性率分别为34.91%(59/169)和4.74%(9/190);鱼和蟾蜍分别为17.33%(13/75)和25.56%(23/90);鸡和鸽子血清中未检测到抗-HEV抗体。结论猕猴、鼠、旱獭、鱼和蟾蜍中存在HEV感染,鼠抗-HEV抗体阳性率最高;其次为蟾蜍和鱼;鸡和鸽子中未检测到抗-HEV抗体。

英文摘要:

To investigate the epidemiology of hepatitis E virus(HEV)infection in macaques,rats,marmots,pigeons,chickens,fish and toads.The anti-HEV antibodies in sera of these animals were detected by using a double-antigen sandwich enzyme immunoassay(DS-ELISA).Of 784 sera collected from these animals,113 were anti-HEV positive,with a positive rate of 14.41 %.The positive rates in sera of macaques,rats,marmots,fish,toads were 7.26%(9/124),34.91%(59/169),4.74%(9/190),17.33%(13/75)and 25.56%(23/90),respectively,while antibody was not detected in sera of pigeons and chickens.These results suggest that macaques,rats,marmots,fish and toads could be infected with HEV,and the highest prevalence rate of anti-HEV was found in rats.

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