中文摘要：

目的探讨痰热清注射液配合常规疗法治疗慢性阻塞性肺疾病（COPD）急性发作的疗效及其作用机制。方法将COPD急性发作期患者随机分为两组,均予西医常规治疗,联用组加用痰热清注射液,观察两组临床疗效并检测患者血清IL-13、LTB-4的含量和肺功能变化。结果联用组显效率明显高于常规组,对血清IL-13、LTB-4及肺功能的改善情况亦优于常规组。结论在常规疗法的基础上联用痰热清注射液治疗COPD急性发作能明显提高临床疗效,这可能与痰热清注射液能明显降低患者IL-13和LTB-4的分泌,减轻由其活化所致的炎症反应,改善肺功能有关。

英文摘要：

Objective：To investigate the effect and the mechanism of the Tanreqing Injection plus routine therapy on acute episode period of COPD.Methods：Acute episode patients with COPD were randomly divided into two groups with routine therapies.The combination group was added the Tanreqing Injection.The IL-13,the LTB-4 and the lung function were detected.The clinical effect was observed.Results：Obvious effects in the combination group were higher than those in the routine group.Meanwhile,in the combination group,the IL-13,the LTB-4 and the lung function improvement were better than those in the routine group.Conclusion：The effect of COPD patients with acute episode can be increased by the routine therapy plus Tanreqing Injection.It may be related to reduction of IL-13 and LTB-4 by Tanreqing Injection which decreases the inflammation reaction and improves the lung function.