中文摘要：

目的：通过动物实验,检测脊柱刚度测试系统（spine stiffness test system,SSTS）的信度。方法：将100只350～450g雄性SD大鼠随机分为5组,分别饲养1、2、4、8、12周,每只大鼠均使用棘突外部连接固定系统对其L4、L5和L6进行外部连接固定。在各自饲养期结束时,使用SSTS进行固定节段的刚度检测,并观察连接时间对大鼠造模节段刚度的影响;为保证SSTS压力测量的准确性,使用前对其压力探头进行标定。结果：SSTS加载探头的实际误差小于0.04%,其误差范围符合实际测试要求;刚度检测结果显示SSTS具有较好的可靠性,组内相关系数ICC=0.948（P〈0.01）,且大鼠造模节段的刚度随连接时间的延长而增加。结论：SSTS具有较好的准确性和可靠性,其控制软件操作简单、易于掌握,可准确采集各点的压力载荷和脊柱运动节段产生的微小位移参数,但在固定辅件的选择、测量范围的确定、干扰变量的区分等方面仍需改进,以便SSTS适用于更多脊柱伤病模型。

英文摘要：

Objective：To investigate the reliability of the spine stiffness test system （SSTS） by animal experiments. Methods：A hundred SD male rats with weight body of 350-450 g were divided randomly into 5 groups according to feeding time of 1,2,4,8,12 weeks. The externally linked fixation systems were implanted into all rats in L4,L5,and L6. At the end of every feeding time,the stiffness of the fixed segment was measured by SSTS,and the relationship between linking time and the stiffness were observed. The parameters of pressure sensor of SSTS were demarcated before measuring the stiffness in order to ensure the accuracy of SSTS. Results：The actual error of the spine stiffness test system was less than 0.04%. Its reliability was good,ICC=0.948 （P0.01）. And the stiffness of the fixed segment increased with linking times. Conclusion：The accuracy and reliability of SSTS were good. Its operating system was very simple to manipulate. And SSTS may accurately collect pressure load and infinitesimal displacement of the spinal motion segment. In order to fit more spinal injuries models,SSTS needs improvements in fixed accessories,measurement range,disturbance variable,and so on.