中文摘要：

龋病是细菌性疾捕，变异链球菌是公认的主要致龋菌。现代龋病学研究认为，浮游变异链球难以在口腔中生存，只有形成牙蔷斑生物膜才可能生存并致龋。大量研究表明，生物膜细菌与浮游细菌在生长代谢、致病性、对药物的敏感性以及对抗宿主防御系统等方面存在显著差异。本文就生物膜状态下变链菌的生物学行为予以综述。

英文摘要：

Caries is a bacterial disease, Streptococcus mutans （S. mutans） is one of the principal bacteria involved in the development of caries. According to modern study on dental earies,S, mutans only survive in plaque biofilms and cause caries. There are much difference between biofilm and planktonic bacteria in the growth and metabolism,pathogens,the sensitivity of the drug against the host defense system. This article reviewed the behavior of S. mutans in biofilm state.