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内质网应激/未折叠蛋白反应促进肿瘤侵袭的研究进展
  • ISSN号:1000-8578
  • 期刊名称:《肿瘤防治研究》
  • 时间:0
  • 分类:R473.6[医药卫生—护理学;医药卫生—临床医学]
  • 作者机构:哈尔滨医科大学附属第一医院手术室,黑龙江哈尔滨150001
  • 相关基金:国家自然科学基金资助项目(81372701)
中文摘要:

目的探讨舒适护理在显微手术治疗额叶胶质瘤手术室护理中的应用效果。方法选取哈尔滨医科大学附属第一医院2013年8月2015年8月收治的90例接受显微手术治疗的额叶胶质瘤患者,采取随机数字表法分为对照组与观察组,每组各45例。对照组仅给予常规护理,观察组在其基础上给予舒适护理,对比两组患者不同时间点心率、血压、白介素-6(IL-6)、皮质醇含量,手术前后焦虑抑郁情绪及术后护理满意度。结果两组T2的收缩压、IL-6及皮质醇含量,T3、T4的IL-6及皮质醇含量比较,差异有统计学意义(P〈0.05)。对照组T2较T1的心率加快,收缩压升高,IL-6、皮质醇含量升高,差异有统计学意义(P〈0.05);对照组T3、T4较T1的IL-6及皮质醇含量升高,差异有统计学意义(P〈0.05)。观察组T2较T1的收缩压升高,IL-6及皮质醇含量升高,差异有统计学意义(P〈0.05);观察组T3、T4较T1的IL-6及皮质醇含量升高,差异有统计学意义(P〈0.05)。两组患者术后焦虑及抑郁评分较术前明显降低,观察组较对照组降低更加显著(P〈0.05)。对照组的护理满意度为68.89%,观察组的护理满意度为93.33%,观察组的护理满意度明显高于对照组,差异有统计学意义(P〈0.05)。结论舒适护理应用于显微手术治疗额叶胶质瘤手术室护理中的效果显著,可平稳生理指标,减少术后焦虑抑郁情绪,提高护理满意度。

英文摘要:

Objective To explore application effect of comfortable nursing in operating room nursing for microsurgical treatment of frontal gliomas. Methods 90 cases with frontal gliomas treated with microsurgery in the First Affiliated Hospital of Harbin Medical University from August 2013 to August 2015 were selected and divided into control group and observation group by taking a random number table method, each group of 45 cases. Routine nursing was used in control group, comfortable nursing was applied in observation group based on control group. Heart rate, blood pressure,IL-6, cortisol levels in different time points, anxiety and depression before and after operation, nursing satisfaction rate after operation between two groups were compared. Results Systolic pressure, IL-6, cortisol levels at T2, IL-6, cortisol level at T3 and T4between two groups were compared, with significant differences(P 〈 0.05). Heart rate at T2 in control group was faster than that at T1, systolic pressure at T2 in control group was higher than that at T1, IL-6, cortisol levels at T2 in control group were higher than those at T1, with significant differences(P 〈 0.05). IL-6, cortisol levels at T3 and T4in control group were higher than those at T1, with significant differences(P 〈 0.05). Systolic pressure at T2 in observation group was higher than that at T1, IL-6, cortisol levels at T2 in observation group were higher than those at T1, with significant differences(P 〈 0.05). IL-6, cortisol levels at T3 and T4in observation group were higher than those at T1, with significant differences(P 〈 0.05). After operation, anxiety and depression scores in two groups were significantly lower than those before operation, observation group was relatively lower than that control group(P 〈 0.05).Nursing satisfaction rate of control group was 68.89%, nursing satisfaction of observation group was 93.33%, nursing satisfaction rate of observation group was obviously higher than that of control group, with significant differe

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期刊信息
  • 《肿瘤防治研究》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国卫生部
  • 主办单位:湖北省卫生厅 中国抗癌协会 湖北省肿瘤医院
  • 主编:魏少忠
  • 地址:武昌卓刀泉南路116号
  • 邮编:430079
  • 邮箱:zlfzyj@263.net.cn
  • 电话:027-87670126
  • 国际标准刊号:ISSN:1000-8578
  • 国内统一刊号:ISSN:42-1241/R
  • 邮发代号:38-70
  • 获奖情况:
  • 中国学术期刊综合评价数据库来源期刊,中国科学引文数据库来源期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,美国剑桥科学文摘,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:17449