中文摘要：

瞬时感受器电位（transient receptor potential,TRP）通道是一类位于细胞膜上的阳离子通道。TRP通道基因最先在研究视觉缺陷的突变体黑腹果蝇中被发现,因其受光刺激仅产生瞬时电生理信号而得名。此后基于序列同源性,在不同动物、酵母和藻类中均有发现,在果蝇中共鉴定得到13个基因,并划分为7个亚家族（TRPC、TRPA、TRPM、TRPV、TRPN、TRPP和TRPML）。TRP通道家族基因在昆虫体内扮演着调控各种生理与行为的重要角色,参与调控昆虫各种感觉的发生,例如视觉、嗅觉、听觉、温度感知以及机械刺激感觉等。近年来的研究表明,TRP家族中TRPV亚家族成员nanchung和inactive基因所编码的蛋白复合物是杀虫剂吡蚜酮的分子靶标。本文分别介绍了TRP通道家族的命名、分类、结构、进化与激活机制等,并结合最新的文献进展对其参与昆虫各种生理与行为功能的研究进行了详细评述。

英文摘要：

Transient receptor potential （ TRP ） channels superfamily of ion channels were first discovered in a mutant of Drosophila melanogaster which were visual defected,it was named by the transient electrophysiological signals when we used the light to stimuli this mutant. Thirteen genes were identified in Drosophila based on the sequence homology, and it was divided into seven subfamilies, TRPC,TRPA,TRPM,TRPV, TRPN, TRPP and TRPML. TRP channels also found in other animals, yeast, alage and so on. TRP superfamily involved in all physiological and sensory modalities in insects, such as vision, olfaction, hearing,thermosensation, mecha- nosensation, etc. Latest research shows that the protein complex of nanchung and inactive which belongs to TRPV subfamily of insect was the target of pymetrozine. In this paper, the nomenclature, classification, structure, evolution and activation mechanism of TRP channel family are introduced respectively, the TRP channels functions of physiological and behavioral in insects are reviewed in detail based on the latest literature.