中文摘要：

目的：探讨肠内免疫营养和生态营养对创伤后大鼠肠免疫功能的影响。方法：将40只大鼠随机分为对照组、普通营养组、免疫营养组和生态营养组。通过胃造口术建立动物创伤模型，给予不同成分的肠内营养7d，观察各组大鼠小肠黏膜形态，检测小肠黏膜中IgA、CD3^＋、CD4^＋、CD8^＋细胞的数量。结果：免疫营养组和生态营养组大鼠术后恢复良好。生态营养组大鼠腹泻累计次数低于普通营养组和免疫营养组（P〈0．05）。三个营养组大鼠的小肠上皮细胞绒毛高度、肠腺隐窝深度、黏膜厚度、绒毛表面积等检测值均优于对照组（P〈0．05）；对照组和普通营养组大鼠小肠黏膜IgA、CD3^＋、CD4^＋、CD8^＋细胞数量明显少于免疫营养组和生态营养组（P〈0．05）。结论：应用肠内营养，特别是肠内免疫营养和生态营养，能较好地改善大鼠的小肠免疫屏障功能，增强肠道免疫功能，促进创伤后的恢复。

英文摘要：

Objective ： To explore the elects of enteral immunonutrition and econutrition on intes-tinal mucosal immune function in wound rats. Methods： Forty Wistar rats were randomly divided into four groups（ control, standard EN, immunonutrition, and econutrition）. Rat models of wound were estab-lished by gastrostomy. The shape of small bowel was observed,IgA CD3^ ＋ ,CD4^ ＋ ,CD8^ ＋ cell quantity of the small bowel mueosa were detected through immunohistoehemical technique. Results： The results showed that enteral immunonutrition group and the eeo-nutrition group recovered well after surgery （P 〈 0.05 ）. The measurements of intestinal villus height, intestinal gland crypt depth, mucosal thickness and villous surface were improved in each enteral nutrition group. The quantity of IgA, CD3^ ＋ , CD4 ^＋ , CD8^ ＋ cell were significantly increased in enteral nutrition groups （ P 〈 0.05 ）. Conclusion ： Enteral nutrition, especially immunization nutrition and eco-nutrition make Wistar rats recover better after injury. Variety of enteral nutrition, especially the intestinal immune nutrition and eco-nutrition, can better improve the intestinal immune barrier function and the intestinal immune function.