中文摘要：

目的了解苏州地区近十年初发急性心肌梗死（AMI）患者性别、年龄、心血管危险因素变化，以及急诊经皮冠状动脉介入治疗（PCI）现状。方法回顾性分析自2006—2015年本院诊断为初发AMI患者，对患者的性别、年龄、心血管危险因素在各时间段的数据进行比较和统计学分析。结果将纳入2511例患者分为五组，2006～2007年度组、2008—2009年度组、2010～2011年度组、2012—2013年度组和2014～2015年度组，各年度组男女比例在4．48～5．49，男性发病平均年龄早于女性。按发病年龄分为四个年龄段：年龄〈45岁、45～59岁、60～74岁和≥75岁。AMI发病高峰年龄段为60～74岁，与同时间段其他年龄段患者构成比比较，差异有统计学意义（P〈0．05）；男性AMI患者发病年龄主要分布在60～74岁，在〈45岁和45～59岁患者构成比呈逐年递增趋势；女性AMI患者发病高峰年龄同男性，在≥75岁呈逐年递增趋势。具有吸烟、高血压危险因素者在AMl人群中始终超过50％，且胆固醇水平居高不下。AMI患者抽吸导管使用率及冠脉内替罗非班使用率逐年增加，行保护性临时起搏器患者比例逐年减少。冠状动脉支架植入术成为主要治疗方法，其次为经皮球囊冠状动脉成形术。结论在苏州地区，AMI患者病例数逐年增加，男性多于女性，男性发病年龄早于女性，有年轻化趋势；吸烟、高血压、高脂血症是主要的心血管疾病的危险因素。因此，在本地区内，加强对心血管危险因素控制，加强对高危人群干预，具有重大意义。急诊PCI是治疗AMI的主要治疗手段。

英文摘要：

Objective To investigate the changes of cardiovascular risk factors in patients with acute myocardial infarction （AMI） and the current status of emergency percutaneous coronary intelvention （PCI） in Suzhou during recent 10 years. Methods The clinical data of patients firstly diagnosed with AMI in our hospital from 2006 to 2015 were analyzed retrospectively. Results 2511 samples were included and divided into 5 groups, 2006- 2007 year, 2008 -2009 year, 2010- 2011 year, 2012 ~ 2013 year and 2014 -2015 year based on admission time. The male to female ratio was in 4.48 ~ 5.49 and the average onset age of male were earlier than women. The patients were divided into 4 age groups according to the onset age： 〈 45 years old, 45 -59 years old, 60 ~ 74 years old and above 75 years old. The peak incidence of age of AMI patients were 60 ~ 74 years old which had significant difference compared with the other age groups in the same age period （P 〈 0.05）. Moreover, the onset age of male patients with AMI was mainly distributed in 60 - 74 years old which were similar with female patients. From 2006 to 2015, the proportion increased gradually in 〈45 and 45 -59 years old in male patients, while in ≥75 years old in female patients. The AMI patients＇ cholesterol was kept in high level, and we also obtained more than half of them had smoking or hypertension. The utilization rate of aspiration catheter and tirofiban increased in patients with AMI by primary PCI, on the contrary, the utilization rate of protective temporary pacemaker decreased. Coronary stent implantation was the main treatment, followed by percutaneous transluminal coronary angioplasty. Conclusion The incidence number of AMI increases gradually; the number of male AMI patients is more than that of female, and the onset age of male is younger than that of female in Suzhou. Moreover, incidence age of male patients with AMI gradually gets younger. Additionally, smoking, hypertension, hyperlipidemia are the main cardiovascular risk factors. Therefor