中文摘要：

目的探讨日光性角化病的临床特征。方法回顾分析1997年1月～2008年12月间病理确诊日光性角化病的临床及病理资料,数据采用Excel整理与分析,用SPSS10.0统计结果。结果1997～2008年共有790851人次的门诊量,取组织病理检查14550例,其中确诊日光性角化病90例,构成比为1.13/万,平均年患病构成比为9.4/十万,以1997至2002年及2003年至2008年前后6年来划分,两阶段确诊病例与确诊未患病例数（χ2=3.934,P〈0.05）、与门诊量之比（χ2=23.751,P〈.001）差异有显著性。男女性别比为1：1.5,发病以农民为多见,发生于50岁以上者占92.12%,平均患病年龄65.94±10.46岁,病程平均2.6年,发生于面部占93.3%,进展成鳞状细胞癌者2例占2.22%。临床诊断与组织病理诊断符合率仅为42.2%,最易误诊为脂溢性角化病、基底细胞癌、色素痣及Bowen病等。结论日光性角化病确诊病例在该院有增加趋势,发病女性高于男性,面部高发,临床易误诊,需引起临床医师高度警惕。

英文摘要：

Objective To study the clinical characters of actinic keratosis.Methods Descriptive epidemiological study was applied to analyze the cases from the dermatology outpatient clinic of the first affiliated hospital of Kunming Medical University form 1997 to 2008. The subjects were all Yunnan population. Excel and SPSS 10.0 were used for data analysis.Results A total of 790851 person-time of outpatient, 14550 biopsy examples and 90 cases of actinic keratosis had been epidermi ologically inestigated from 1997 to 2008. The average constituent ratio of actinic keratosis was 1.13/10 000,and the annual constituent ratio was 9.4/100 000.The onset of actinic keratosis increased with aging. There was a distinct characteristic of seasonal difference.The ratio of male/female was 1：1.5. The patients’ages ranged from 33 to 85 years old and the average was 65.94±10.46 years. 92.2% patients Presented the macules after 50 years old and more. The average of course of actinic keratosis was 2.6 years. The macules were located in face in 83 cases（93.3%）, in the cheek in 44 cases（48.9%）,2 cases（2.2%） had squamous cell carcinoma. The diagnostic accordance rate between clinic and pathology was only 42.2%. Conclusion The confirmed cases of actinic keratosis were slowly increasing. Actinic keratosis was most than in meles in females in Yunnan people. The misdiagnosis often happened in clinical works.