在《细胞》和《自然》发表的ChIP-chip和BS-Seq技术是基因组甲基化图谱构建的两个重要里程碑.分析了它们的特点、优势与不足,并对此作了进一步探讨.
The techniques of ChIP-chip and BS-Seq issued on the Cell and the Nature are two most important milestones for mapping genomic methylation.Analyses their features,advantages and disadvantages,and proposed the further exploration.