胰腺癌是临床上常见的一种消化道恶性肿瘤,近年来其发病率呈上升趋势。该文从抑癌基因DPC4的起源、结构和功能、抑癌基因DPC4对胰腺癌的调控机制等角度对抑癌基因DPC4与胰腺癌的关系进行综述。
Pancreatic cancer is a common malignant tumor of the alimentary canal in the clinic. Its incidence is rising in recent years. In this summarization, origin, construction and function of deleted pancreatic carcinoma 4 are summarized. And the regulation mechanism on deleted pancreatic carcinoma 4 in pancreatic cancer is summarized.