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基于非生物折叠体的分子识别
  • 期刊名称：有机化学, 2007, 27 (2), 188-196.
  • 时间：0
  • 分类：O641.3[理学—物理化学;理学—化学]
  • 作者机构：[1]复旦大学化学系,上海200433, [2]中国科学院上海有机化学研究所生命有机化学国家重点实验室,上海200032
  • 相关基金：国家自然科学基金（Nos.20321202,20572126,20372080,20332040,20425208）资助项目.
  • 相关项目：分子间相互作用及分子聚集体中的化学反应
作者： 李昌治,蒋锡夔, 黎占亭, 高翔,
关键词： 分子折叠体, 分子识别, 氢键, 疏溶剂作用, 二级结构, foldamer, molecular recognition, hydrogen bonding, hydrophobic interaction, secondary structure
中文摘要：

利用分子自组装的方法控制大分子量的线性有机分子的构象是物理有机化学一个富于挑战性的研究课题．近年来．化学家已经成功利用不同的分子内非共价键作用力如氢键和疏溶剂作用等诱导线性分子的折叠乃至螺旋构象的产生．综述了近年来这种新的非生物二级结构形式在分子识别研究中的应用．

英文摘要：

One of the challenging fields in physical organic chemistry is the control of the conformation of large linear organic molecules. In recent years, different non-covalent forces, especially hydrogen bonding and hydrophobic interaction, have been successfully applied to induce the folded or helical conformations of linear organic molecules. This paper reviews the recent applications of this new class of non-biological secondary structures in molecular recognition.

同期刊论文项目
物理有机化学
期刊论文 35 著作 1
有机分子基组团定位和功能的非共价键控制
期刊论文 25 著作 1
化学生物学导向的有机合成
期刊论文 164
有机分子的有序簇集和卷曲
期刊论文 11
分子间相互作用及分子聚集体中的化学反应
期刊论文 102 会议论文 26 获奖 2 著作 2
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