中文摘要：

本文研究了盐酸环丙沙星（Cipro）在导电碳黑糊电极上的伏安行为,结果表明：B-R 缓冲溶液（pH 4. 0）中,该药物分子发生2 质子、2 电子转移的不可逆电化学氧化,过程受吸附控制,电子转移系数α 为0. 37,表面反应标准速率常数k′s为0. 95 s-1 .实验研究了支持电解质种类、pH 值、离子强度、富集电位与时间等对其伏安响应的影响,并据结果对检测条件进行优化,进而建立了Cipro 的电化学检测方法.优化条件下,Cipro 的氧化峰电流（ipa）与其浓度（C0 ）在2. 5×10-7 -6. 0×10-5 mol·L^-1 范围内呈良好的线性关系,检测限为9. 5×10-8mol·L^-1（S / N =3）.将该方法应用于测定淡水渔业水样中痕量Cipro,得到了较满意的结果（平均回收率102. 73%）.

英文摘要：

The electrochemical behaviors of ciprofloxacin hydrochloride(Cipro)were investigated by voltammetry using conductive carbon black paste electrode as working electrode. Results indicate that an irreversible adsorption-controlled oxidation reaction of Cipro occurre in the B-R buffer solution of pH 4. 0 with two protons and two electrons transfer. The electron transfer coefficientαis 0. 37 and the standard surface reaction rate constant k′s is 0. 95 s-1 . Effect factors,including species of the supporting electrolyte, pH,ionic strength of supporting electrolyte,accumulation potential and accumulation time,were studied and optimized. Under the optimal conditions,there is a linear relationship between the oxidative peak current of Cipro and its concentration over the range of 2. 5 × 10-7 ~6. 0 × 10-5 mol·L-1 with a detection limit of 9. 5 × 10-8 mol·L-1(signal/noise=3). The method was applied to de-termine trace Cipro in real fishery water samples. And the outcomes were satisfactory with an average recovery rate of 102. 73%.