目的探讨胚胎停育患者在生活和lT作中接触环境的危险因素。方法采用病例.对照研究,于2008年7月1日一2009年5月1日北京市某区妇幼保健院进行问卷调查,了解个人基本情况、环境中接触到的可疑的危险因素、生殖保健知识、婚检等情况。选择253例确诊的胚胎停育孕妇为病例组,同期239例正常妊娠者为对照。结果非条件Logistic回归分析表明工作场所、家庭通风情况(OR=0.514),孕早期使用手机、电脑的时间(OR=2.266),月经量(OR=-1.552),孕前、孕期获得生殖保健服务(OR=-1.384),急性感染(OR=2.074)可能与胚胎停育的发生有关。结论孕妇居室通风,孕前、孕期获得生殖保健服务,婚检可能是预防胚胎停育的保护性因素,孕期使用手机、电脑,妊娠前3个月急性感染可能是胚胎停育发生的危险因素。
Objective To investigate the potential factors related to the induction of missed abortion in living and working environment. Methods Based on case-control design, 253 pregnant women with missed abortion were selected as the case group, while 239 women with normal pregnancy as the control group. The data were analyzed by X2 test, t-test and logistic regression respectively. Results Logistic regression analysis revealed that ventilation status of living room (0R=0.514), using time of mobile phone, computer (0R=2.266), menstrual blood volume (0R=-1.552), acquiring the knowledge of prevention health service (OR =-1.384), and acute infection (OR =2.074) might be related to missed abortion. Conclusion Ventilation and access to reproductive health care services, knowledge, pre-marital health examination are the protective factors for missed abortion. Acute infection and the use of mobile phone, computer time may be the risk factors for missed abortion.