中文摘要：

以三聚氯氰为起始原料,合成了系列新的含嘧啶氨基的2,4,6-三取代-1,3,5-三嗪化合物,并测试了化合物抗苹果树腐烂病菌和抑制肿瘤细胞增殖活性.结果表明,化合物2aa～2cb及3aa～3cb对苹果树腐烂病菌具有显著的抑制作用,具有开发为新型植物抗菌剂的潜力.部分化合物,如4ba和4ca分别对胃癌（BGC-823）和宫颈癌（Hela）肿瘤细胞具有较强的抑制活性,IC50分别为10.9和11.3μmol/L.

英文摘要：

A series of novel trisubstituted 1,3,5-triazine compounds bearing aminopyrimidine group were synthesized using cyanuric chloride as the starting material. The antifungal activitiy against Valsa mall and antiproliferative activity for three tumor cells of all the triazine compounds were evaluated. The results showed that a majority of the compounds 2aa~2cb and 3aa~3cb have notable inhibitory activity against Valsa mall Some compounds, such as 4ba and 4ca, showed good cytotoxicity to BGC-823 and Hela tumor cells with the IC50 value of 10.9 and 11.3 ~tmol/L, respectively, higher than that of the positive control cis- platin.