中文摘要：

目的：探讨动脉瘤性蛛网膜下腔出血（a SAH）介入治疗患者肠道屏障功能的变化及与膳食能量摄入的相关性,为护理人员对术后患者进行膳食营养指导提供依据。方法：共纳入35例患者,在其术后1、3、7、14 d时采集空腹血。用于检测二胺氧化酶（DAO）、D-乳酸（DLC）、内毒素（EN）。并每天记录患者的膳食能量摄入情况。结果：患者DAO、DLC、EN水平第7天达峰值（P〈0.05）,14 d有所下降。术后4~7 d摄入的膳食能量与术后3 d的血浆DAO水平呈负相关。术后7~14 d膳食能量摄入与术后14 d的血浆DLC水平呈负相关。结论：a SAH介入治疗患者DAO、DLC、EN水平第7天达峰值;禁食时间与肠道屏障功能成负相关,肠道屏障损伤程度与患者膳食能量摄入量呈正相关。

英文摘要：

Objective： To investigate the correlation between the changes of intestinal barrier function and the dietary energy intake in patients underwent intervention treatment for aneurysmal subarachnoid hemorrhage（ a SAH）,and to provide basis for nurses to give dietary nutrition guidance to postoperative patients. Methods： A total of 35 patients were selected and fasting blood was collected at 1,3,7 and 14 days after operation for detection of diamine oxidase（ DAO）,D-lactic acid（ DLC） and endotoxin（ EN）. And the patient＇s dietary energy intake was recorded every day. Results： The levels of DAO,DLC and EN of the patients were peaked on the 7th day（ P〈0. 05） and decreased in 14 days after the operation. The dietary energy intake at 4-7 days after operation had a negative correlation with plasma DAO level at 3 days after operation. There was a negative correlation between dietary energy intake at 4-14 days after the operation and plasma DLC level at 14 days after operation. Conclusion： The levels of DAO,DLC and EN in a SAH intervention patients reached the peak at the 7th day after operation. The fasting time was negatively correlated with intestinal barrier function,and the degree of intestinal barrier injury was positively correlated with dietary energy intake of the patients.