中文摘要：

研究神经电极对软组织的植入损伤问题,关系到神经电极的长期寿命。基于内聚力单元,建立了神经电极植入软组织过程数值仿真模型;通过单轴拉伸试验并对软组织Ⅰ型裂纹体进行柔度测定,获得了组织基体超弹性力学本构和能量释放率。结果表明：植入损伤随能量释放率增加而显著增加;随着电极楔形角增加,植入损伤先增大后降低;外凸流线型电极相比于直线型与内凹型更有利于减少组织植入损伤。仿真结果可为新型神经电极植入参数设计提供参考,从而减少组织植入损伤,提高电极工作寿命。

英文摘要：

The investigation of neural probe＇ s insertion induced tissue injury is related to the longevity of the probe.A numerical simulation model of neural probe insertion into soft tissue is developed based on cohesive element model.By uniaxial tension experiments and compliance calibration of soft tissue with Mode I crack,hyper-elastic constitutive model and energy release rate are obtained.The simulation results show that tissue injury increases significandy with the increase of energy release rate：As the wedge angle increases,tissue injury increases first and then decreases：Probe with convex streamline generates less injury than that with straight or concave streamline.The simulation results could be helpful for the optimal design of insertion parameters and helpful for reducing insertion induced tissue injury and thus can improve the long-term stability of the neural probe.