中文摘要：

这里，我们在偏爱和 mRNA secondary 上报导鳕鱼红血球凝聚素的结构的特征(哈) 劈开地点鸟的流行性感冒病毒 H5N1 子类型的基本氨基酸区域。我们开发了动态扩大合拢的策略在反复的扩展进程用 RNAstructure 4.1 节目预言 RNA 第二等的结构。序列的统计分析证明 HA 劈开地点基本氨基酸宠爱充满腺嘌的鳕鱼 ons，和相应 mRNA 碎片主要处于搁浅单人赛的环的合拢的状态。我们的顺序、结构的分析显示了那阻止并且控制这些高度病原的病毒，也就是说禁止鸟的流行性感冒病毒 H5N1 子类型的基因表示，我们应该作为 RNA 干扰的目标认为 HA 劈开的搁浅单人赛的环区域是编码地点的序列。

英文摘要：

Here we report the codon bias and the mRNA secondary structural features of the hemagglutinin （HA） cleavage site basic amino acid regions of avian influenza virus H5N1 subtypes. We have developed a dynamic extended folding strategy to predict RNA secondary structure with RNAstructure 4.1 program in an iterative extension process. Statistical analysis of the sequences showed that the HA cleavage site basic amino acids favor the adenine-rich codons, and the corresponding mRNA fragments are mainly in the folding states of single-stranded loops. Our sequential and structural analyses showed that to prevent and control these highly pathogenic viruses, that is, to inhibit the gene expression of avian influenza virus H5N1 subtypes, we should consider the single-stranded loop regions of the HA cleavage site-coding sequences as the targets of RNA interference.