中文摘要：

目的：探讨民族药铁棒锤不同炮制品中各元素的种类及含量。方法：利用电感耦合等离子体发射光谱法（ICP-AES）、原子吸收光谱法（AAS）和原子荧光光谱法（AFS）全面扫描并分析民族药铁棒锤生品及其8种不同炮制品中与人体健康和生命相关的常量元素、微量元素和重金属的种类及含量。结果：从铁棒锤中共检测出22种元素,与生品相比,不同炮制方法使某些元素发生了明显不同的变化,表明元素变化与炮制方法有较强的相关性。结论：3种光谱分析方法均能快速准确地分析药材中各种元素含量及其变化趋势,说明炮制和辅料不仅能改变元素含量而且能与有效成分一道发挥协同治疗疾病的效果,并发现藏医和羌医的炮制方法将导致重金属Hg的含量急剧增高,临床使用铁棒锤时存在安全隐患。实验拓宽了光谱法在中药安全性评价中的应用。

英文摘要：

Objective：To investigate the kinds and contents of elements in different fried Aconitum pendulum Busch.Methods：ICP-AES,AAS and AFS were used to scan and analyze macro elements,trace elements and heavy metals which were correlated with people＇s health and lives in A.pendulum Busch and its eight different fried samples for the first time.Results：Twenty two elements were found in A.pendulum Busch,and there had been noticeable changes of the contents of some elements in fried samples comparing with samples fried with nothing.Conclusion：Three kinds of analyzing methods could be used to judge the contents of all elements and their changing trends in traditional Chinese medicine quickly and truly.These results indicated there had been great relevance between changes of elements and different frying methods,and auxiliary materials can not only change the contents of elements but also play a role in treating ills along with effective constituents.Also,it was found the content of Hg rose greatly in Tibetan medicine and Qiang medicine,and these showed there was potential safety hazard when it was used.These experiments widen the application of spectrum analyzing methods on safety evaluation of traditional Chinese medicine.