中文摘要：

信息时代由于信息量巨大,传统的生物学讲学模式易导致知识片段化和浅表化等问题,从而显得乏味。应用生物信息学由于具有在实践中串并联相关知识点的特征,可成为转变这些问题的重要利器。为利用好这把利器,本文探讨了应用生物信息学课程的系统化综合性教学改革。论文从教学内容系统性布局（课程定位、内容结构和教学手段）和综合解析优秀科普视频中趣味性生物学问题两方面,图文并茂地展示了改革实践。实践中学生们受益匪浅。学生综合素质的提升体现在很多方面,比如认知的系统性与深度提高、思维模式由被动转变为主动、团队合作意识增强、学习兴趣热情提升、克服困难的勇气与自信心增强、自主设计与创新能力提升等。信息时代的生命科学已由传统的实验性科学转变为由思维分析主导的实验设计兼由设计主导的实验论证性科学,而应用生物信息学课程正是训练信息时代相关科研能力的重要环节。论文实施的系统化综合性教学改革取得了一定成效,值得借鉴与交流。

英文摘要：

Facing huge information, the traditional lecturing mode encountered lots of problems regarding knowledge fragmentation and plainness, which makes study boring. Applied Bioinformatics is an important tool for connecting knowledge points and can be utilized to solve the problems. To utilize well, this paper discussed the systematic and comprehensive reforms of the Applied Bioinformatics Course. This paper illustrated the teaching reforms that covered two aspects： the systematic outline of teaching contents and the comprehensive analysis of biological topics from popular science video. Based on feedbacks, students benefit a lot from the reforms and many aspects oftheir qualities were promoted. In the current information age, life science has been changing from the traditional experimental science to the rational design and experimental verification science, which dominated by thinking and analyzing. The Applied Bioinformatics course plays an important role in training such kind of research abilities. The systematic and comprehensive teaching reforms have made certain achievements, which has worth of learning and communicating.