目的研究针刺治疗硝酸甘油偏头痛大鼠模型的行为学改变。方法将成年雄性SD大鼠32只,随机分为空白组、皮下注射硝酸甘油模型组、皮下注射生理盐水模型对照组、皮下注射硝酸甘油+电针治疗观察组4组。实验第0天测定痛阈基线,第1、2、3天分别处理并测定各组大鼠痛阈。结果模型对照组痛阈与空白组比较,差异无统计学意义(P〉0.05);模型组较模型对照组痛阈下降,差异有统计学意义(P〈0.05);观察组痛阈高于模型组,差异有统计学意义(P〈0.05)。结论针刺对偏头痛有治疗作用。
Objective To study the behavioral changes of rat modal with Nitroglycerin migraine treated with acupuncture. Methods 32 Male SD rats were randomly divided into four groups, including blank group, subcutaneously injected Nitroglycerin model group, subcutaneously injected saline model group and subcutaneously injected Nitroglycerin + electro-acupuncture treatment observation group. On day 0, pain threshold baseline was tested. On day 1, 2, 3, pain threshold of all groups were processed and tested. Results Compared with the blank group, the difference of pain threshold of model control group was not statically significant (P 〉 0. 05 ) . The pain threshold of the model group was more declined than that of the control group, the difference was statistically significant (P 〈 0.05) ; compared with the model group, the pain threshold of observation group was higher than that of the model group, the difference was statistically significant (P 〈 0. 05) . Conclusion The electro-acupuncture has therapeutic effect on migraine.