中文摘要：

目的：观察腰椎融合术结合腰椎间融合器植入对腰椎退行性疾病的治疗效果及对预后评估。方法：选择我院2013年1月至2014年1月收治的54例腰椎退行性疾病患者为研究对象,随机将其分为两组,对照组患者行单纯椎间植骨融合术,实验组患者给予腰椎融合术结合腰椎间融合器植入治疗,对两组患者的手术时间、手术失血量、住院天数、融合率及并发症情况进行观察,同时对术前、术后三个月均应用VAS评分、ODI评分评估患者恢复情况。结果：实验组融合率明显高于对照组,但实验组手术时间较对照组长,差异具有统计学意义（P〈0.05）;两组术中出血量及住院天数无统计学意义（P〉0.05）;与术前比较,两组患者VAS评分、ODI评分均明显降低,差异具有统计学意义（P〈0.05）;与对照组比较,实验组术后VAS评分和ODI评分降低更明显,差异具有统计学意义（P〈0.05）;疗效与并发症比较,实验组优于对照组（P〈0.05）。结论：腰椎融合术结合腰椎间融合器植入治疗腰椎退行性疾病临床疗效显著且安全性高,对患者预后较好。

英文摘要：

Objective： To observe the effect of lumbar interbody fusion combined with lumbar interbody fusion cage in treatment of lumbar degenerative disease and the evaluation of prognosis. Methods： 54 cases of lumbar degenerative disease patients in our hospital from January 2013 to January 2014 were as the research objects, then were randomly divided into two groups. The patients in the control group underwent intervertebral bone grafting, and the patients in the experimental group received lumbar interbody fusion combined with lumbar interbody fusion cage implantation. The operative time, operative blood loss and the days of hospitalization, fusion rate and com- plications were observed. At the same time of preoperative and postoperative three mouths, VAS score and ODI score were applied to evaluate the recovery of patients. Results： After treatment, the fusion rate in experimental group was 96.3 %, higher than 81.48 % of the control group （P〈0.05）. No one postoperative complication in the experimental group was detected but 2 cases occurred in the control group, and the incidence rate of complications was significantly lower in the experimental group, but the operation time of the experi- mental group was longer than that of control group （P〈0.05）; there was no statistical significance in the amount of intraoperative hemor- rhage and the days of hospitalization between the two groups （P〉0.05）. After treatment, the VAS score and ODI score were significantly decreased, and it was more significant in the experimental group compared with control group （P〈0.05）; in the comparison of the efficacy and complications, the experimental group was superior to the control group, P〈0.05. Conclusions： Lumbar interbody fusion combined with lumbar intcrbody fusion cage has significant clinical therapeutic effect, high safety and good prognosis for the lumbar degenerative disease.