中文摘要：

动物黏液是动物分泌和黏附于体内或体表（外）各种表面的湿滑液体,多为浓稠的胶状体,主要成分为黏蛋白、无机盐,并含有抗菌物质如溶菌酶、免疫球蛋白,在作为生物体保护性屏障和润滑作用方面具有重要作用.近五年来,随着现代生物学理论和研究技术的快速发展,对于动物黏液的生物效应和作用机制尤其是屏障效应和黏附机制等方面的研究取得了长足的进步.这些研究表明,在分子层面决定动物黏液屏障效应和黏附机制的关键在于黏液的化学成分如黏蛋白以及相应的物理特性.本文介绍了近年来与动物黏液的屏障效应和黏附机制相关的研究,主要包括动物黏液的生物效应、研究方法、化学组成、物理性质、作用机理等方面的研究进展.

英文摘要：

In animals, mucus is a common slippery internal or external secretion. Mucus is mainly composed of mucins and inorganic salts. Some antibacterial agents, such as lysozymes and immunoglobulin are also found in mucus. Mucus plays an important role in body lubrication and defense. Early research focused on compositional and functional analysis of mucus. In the last 5 years, rapid development of theories and techniques in modern biology have enabled study of mucus and relevant applications at the molecular level, especially involving barrier effects and adhesion mechanisms. The chemical composition of mucus, such as mucins, contributes to the biological effects and physical properties of mucus in animals. In this article, we briefly introduce the latest approaches in barrier effect and adhesion mechanism research of mucus in animals, including biological generation and the function of mucus, research methodology, chemical composition, physical properties and mechanisms of mucus.