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Waist Circumference-dependent Peripheral Monocytes Change after Gliclazide Treatment for Chinese Type 2 Diabetic Patients
  • 时间:0
  • 分类:R587.1[医药卫生—内分泌;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]苏州大学医学院,苏州215000, [2]上海交通大学附属第六人民医院内分泌与代谢科,上海市糖尿病研究所,上海200233, [3]上海市奉贤区中心医院普外科,201400
  • 相关基金:国家自然科学基金(81322010)
中文摘要:

外科手术已被认可为治疗2型糖尿病(T2DM)的一种新型方式,其中胃转流术是目前备受关注的手术方式,并逐渐进入临床。胃转流术治疗T2DM效果显著,尤其适用于伴肥胖的T2DM患者,甚至可以达到有效控制血糖及缓解糖尿病并发症的目的。然而,其潜在作用机制复杂,主要包括胃肠激素分泌的变化、脂肪因子的作用、胆汁酸代谢等。

英文摘要:

Surgery has beenaccepted as a newapproach for the treatment of type 2 diabetes mellitus (T2DM).At present,gastric bypass is thehigh-profileoperation methodandgradually appliedclinically. It showed significant effect in the treatment ofT2DM, especially for the T2DM patients accompanied with obesityandeven achieve the purposeto control blood glucose and its complications.However, the underlying mechanism of gastric bypass in treatingT2DM isquitecomplex, including the changesin gastrointestinal hormones, the action of fat factor,bile acid metabolism,etc.

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