中文摘要：

以便利用 polypyrrole (PPy ) 的应用在生物传感器和生物电子的衍生物， biomolecules 的不同固定机制到上不同地，进行 PPy 电影的 functionalized 被调查。有 carboxyl 和氨基的组的吡咯和吡咯衍生物被化学聚合的方法与在 Au 表面上自我装配的 -(N-pyrrolyl)-octylthiol 异分子聚合形成共聚物电影的层，即， poly [pyrrole-co-( N-pyrrolyl ) -caproic 酸]( poly ( Py-co-PyCA ))并且 poly [pyrrole-co-( N-pyrrolyl )-hexylamine]( poly ( Py-co-PyHA ))，在哪个 carboxyl 组在( Py-co-PyCA ) poly 被激活到酉旨组。基于结构特征， PPy 上的 DNA 分子的固定 / 杂交， poly (Py-co-PyCA ) 并且(Py-co-PyHA ) 被周期的 voltammograms 大小 poly 调查。为不同地 functionalized 共聚物， DNA 的固定机制是各种各样的。在前后，而且， PPy 和它的共聚物的合成电极的电气化学的性质正在被检测牛的浆液白朊(BSA ) 吸附，蛋白质绑定的运动过程被光谱学的表面电浆子回声决定。因为很少 BSA 分子能抛锚到 PPy 和它的共聚物表面上，它建议这种进行的聚合物能作为蛋白质抵抗的材料被使用。

英文摘要：

In order to exploit the applications ofpolypyrrole （PPy） derivatives in biosensors and bioelectronics, the different immobilization mechanisms of biomolecules onto differently functionalized conducting PPy films are investigated. Pyrrole and pyrrole derivatives with carboxyl and amino groups were copolymerized with ω-（N-pyrrolyl）-octylthiol self-assembled on Au surface by the method of the chemical polymerization to form a layer of the copolymer film, i.e., poly[pyrrole-co-（N-pyrrolyl）-caproic acid] （poly（Py-co-PyCA）） and poly[pyrrole-co-（N-pyrrolyl）-hexylamine] （poly（Py-co-PyHA））, in which the carboxyl groups in poly（Py-co-PyCA） were activated to the ester groups. Based on the structure characteristics, the immobilization/hybridization of DNA molecules on PPy, poly（Py-co-PyCA） and poly（Py-co-PyHA） were surveyed by cyclic voltammograms measurements. For differently functionalized copolymers, the immobilization mechanisms of DNA are various. Besides the electrochemical properties of the composite electrodes of PPy and its copolymers being detected before and after bovine serum albumin （BSA） adsorption, the kinetic process of protein binding was determined by surface plasmon resonance of spectroscopy. Since few BSA molecules could anchor onto the PPy and its copolymers surfaces, it suggests this kind of conducting polymers can be applied as the protein-resistant material.