中文摘要：

目的探讨γ-谷氨酰转肽酶与血压的关系。方法采用横断面研究，收集自然人群样本1480例，采用问卷调查吸烟、饮酒以及服药情况，测量身高、体重、血压等，空腹抽血检测γ-谷氨酰转肽酶、血糖、血脂、肝功能、肾功能等相关指标。结果1480名居民中男性886名，女性594名，年龄20—84岁。Pearson相关分析发现，γ-谷氨酰转肽酶与收缩压、舒张压、总胆固醇、血糖、低密度脂蛋白胆固醇、血尿酸、血肌酐以及体质指数正相关，而与高密度脂蛋白胆固醇负相关。对log转换的γ-谷氨酰转肽酶水平的四分位数分析发现，四组间年龄、收缩压、总胆固醇、血糖、天冬氨酸氨基转移酶、丙氨酸氨基转移酶水平有显著差异，尤其是最高四分位数水平显著升高。Logistic回归分析发现，在调整上述协变量之后，最高位四分位数和最低位四分位数相比高血压患病风险增高74％（OR=1．74，95％CI为1．13～2．68，P=0．01）。结论叫．谷氨酰转肽酶水平与血压水平正相关，且可预测高血压。

英文摘要：

Aim To explore the correlation between serum γ-glutamyl transferase （-y-GT） and blood pressure. Methods 1480 subjects were enrolled in the cross-sectional study, and standard questionnaire was used to collect informa- tion on smoking, alcohol intake and medication. Fasting blood was drawn to test γ-GT, serum glucose, liver and renal function, and body weight, body height and blood pressure were measured. Results 1480 subjects included 886 male and 594 female with age range from 20 to 84 years old. By Pearson correlation analyses, γ-GT was positively correlated with systolic blood pressure, diastolic blood pressure, total cholesterol, serum glucose, low density lipoprotein cholesterol, serum uric acid, serum creatinine and body mass index, and negatively correlated with high density lipoprotein cholesterol. Compared with the lowest quartile, the highest quartile had significantly higher level of systolic blood pressure, diastolic blood pressure, total cholesterol, serum glucose, alanine aminotransferase and aspartate aminotransferase. After adjust- ment of sex, age, body mass index, current smoking, current alcohol intake, Logistic regression analysis indicated that there was a 74% higher risk of hypertension when compared the highest quartile with the lowest quartile （ OR = 1.74, 95% CI was 1.13 - 2. 68, P = 0. 01 ）. Conclusion γ-GT was positively correlated with blood pressure and can predict hy- pertension in Chinese.