中文摘要：

研究了两亲性无规共聚物聚（苯乙烯-co-甲基丙烯酸）（P（St-co-MAA））（单体摩尔比分别为6∶4和7∶3）自组装胶束的物理化学性质，及其作为假固定相（ PSP）的胶束电动色谱性能。测定了聚合物胶束的临界胶束浓度（ CMC），对胶束内核微环境的极性、表面电荷密度和流体力学直径等微结构参数进行了表征，对时间窗口、亚甲基选择性等电动色谱参数进行了测定，并与聚（甲基丙烯酸甲酯-co-甲基丙烯酸）（P（MMA-co-MAA））胶束、十二烷基硫酸钠（ SDS）胶束体系进行了比较；利用线性溶剂化能关系（ LSER）研究了聚合物PSP的选择性差异。结果表明：P（ St-co-MAA）体系具有最小的CMC、最宽的时间窗口和最好的亚甲基选择性；LSER表明，疏水作用是决定聚合物PSP选择性的最主要因素，氢键酸度其次，特别是P（ St-co-MAA）（单体摩尔比7∶3）体系具有最高的作用参数，显示了该PSP具有较高的分离选择性。

英文摘要：

The amphiphilic copolymer poly （ styrene-co-methacrylic acid ） （ P （ St-co-MAA ） ） with molar ratios of 6∶4 and 7∶3 self-assembled to form micelles. The polymeric micelles were used as pseudostationary phase （ PSP ） in micellar electrokinetic chromatography （ MEKC ） . Their physicochemical properties and MEKC performance were investigated as well in the pres-ent work. The critical micelle concentration （ CMC ） , polarity, surface charge density and hydrodynamic diameter were used to characterize the solution physicochemical properties, while the methylene group selectivity was evaluated with n-alkylphenone homologous series. The time window and linear solvation energy relationship （ LSER） analysis were used to charac-terize the MEKC retention behavior and the selectivity. All of these were compared with poly （ methyl methacrylate-co-methacrylic acid ） （ P （ MMA-co-MAA ） ） with the molar ratio of 7∶3 and sodium dodecyl sulfate （SDS） micellar systems. The results showed that P（St-co-MAA） system had the minimum CMC, the widest time window and the best methylene group selectivi-ty . LSER analysis results showed that the hydrophobic effect was the most important interaction between solutes and PSPs, and the hydrogen-bonding acidity was the second significant factor on selectivity and MEKC retention behavior. P（ St-co-MAA） system, especially with the molar ratio of 7∶3, had the highest effective parameter in LSER and showed a high separation selectiv-ity of PSP.