中文摘要：

目的应用斑点追踪显像（STI）技术评价主动脉瓣狭窄（As）患者经导管主动脉瓣植入术（TAVI）后左心室收缩功能的变化，并分组评价二叶式主动脉瓣（BAV）和三叶式主动脉瓣（TAV）患者术后变化。方法选取29例于我院行TAVI术的AS患者，采集术前、术后3d、术后1个月常规超声心动图检测指标，并分别采集二维及三维图像，运用Olab软件分析纵向收缩期峰值应变（LS）、周向收缩期峰值应变（cs）、三维超声左室射血分数（3I）ILVEF）等指标，并比较各时间节点的变化。结果术后主动脉瓣前向血流速度（AV）、主动脉瓣最大跨瓣压差（AVPCrmax）、主动脉瓣平均跨瓣压差（AVPG-mean）、主动脉瓣瓣口面积（AVA）均有明显改善。术后3d整体纵向收缩期峰值应变（GLS）在BAV组、TAV组均有明显改善（均P〈0．001），术后1个月有进一步改善（均P〈0．001）。整体周向收缩期峰值应变（GCS）术后1个月较术前有明显改善（P〈0．001）。术后3d3D-LVEF无改善，术后1个月较术前有改善（P〈0．001）。所有检测指标中，BAV患者和TAV患者变化趋势一致。结论TAVI术后早期左心室收缩功能已经有所改善，并随随访时间延长进一步恢复，BAV患者行TAVI术能与TAV患者同等获益。

英文摘要：

Objective To evaluate the left ventricle systolic function in patients with aortic stenosis （AS） underwent transcatheter aortic valve implantation（TAVI） by speckle tracking imaging and to observe the indicators in bicuspid aortic valves（BAV） and tricuspid aortic valves（TAV） groups. Methods Twenty- nine patients with AS were enrolled, all of them underwent TAVI successfully. The regular echocardiography and 3D full-volume images were acquired on before and 3 days, 1 month after TAVI. Longitudinal strain, circumferential strain, and three-dimensional left ventricle ejection fraction（3D-LVEF） were analyzed using Qlab software. Results Compared with the baseline, aortic valve blood flow velocity （AV）, maximum aortic valve pressure gradient （AVPG,-max）, mean aortic valve pressure gradient （AVPCr- mean）, aortic valve area（AVA） after TAVI were improved significantly. Global longitudinal strain（G-LS） had a improvement on 3 days after TAVI（all P d0. 001）, and further increased during 1 month after TAVI （all P d0.001）. Global circumferential strain（GCS） were increased during 1 month after TAVI（all P 0.001）. The 3D-LVEF after 1 month were improved significantly（all P 〈0.001）. The BAV patients and TAV patients had similar changes in all of indicators observed. Conclusions The left ventricle systolic function has early improvement after TAVI, and further recovery during follow-up. The BAV patients can obtain a benefit from TAVI equally to the TAV patients.