中文摘要：

目的探讨青少年SLE患者发病的临床特征,为开展有效救治,以改善预后、提高生活质量提供参考。方法选取1997年1月-2007年12月在蚌埠医学院附属医院风湿科住院且资料较完整的6-18岁患者66例的病例进行分析。将病例资料输入Epi Data数据库,采用SPSS13.0软件进行统计学处理。结果首发症状以关节痛最为常见（47.0%）,其次是发热（42.4%）和皮疹、红肿（34.8%）。在血液学指标中,除ESR阳性、CRP阳性和抗ds-DNA阳性检出率各组之间差异均有统计学意义外（P〈0.05或P〈0.01）,其余各组之间差异均无统计学意义（P〉0.05）。ESR水平在各组之间的差异有统计学意义,而CRP差异无统计学意义。结论青少年SLE患者的首发症状较为隐蔽,其诊断必须辅以相应的血液指标检验结果。

英文摘要：

Objective To study the nosopoletic clinical characteristics of the SLE adolescent patients, and provide reference for developing effective treatment, improving prognosis and life quality. Methods 66 SLE adolescent patients in the Affiliated Hospital of Bengbu Medical College from January 1997 to December 2007. The questionnair wqsinput to Epi Data database and then read by SPSS 13.0 statistic software. Results Arthralgia was the first symptom （47.0%）, others being fever （42.4 % ） and erythra （34.8 % ）. The positive rates of ESR, CRP and ds-DNA had obvious differences in each group, and the ESR level in each group had significant difference too. Conclusions The first symptom of the SLE adolescent patients is more hidden, and its diagnosis must be combined with clinical test .