中文摘要：

目的探讨小儿重度感染性脑损伤与心肌酶谱以及预后的相关性,为临床治疗和护理提供依据。方法选取医院2012年5月-2013年6月收治的70例重度感染性脑损伤患儿作为研究对象,根据格拉斯哥昏迷评分（GCS）将患儿分为3-5分组37例和6-8分组33例,另选35名健康儿童作为对照组;测定105例儿童检测当天的心肌酶含量,分析脑损伤程度与心肌酶的相关性;根据患儿的预后将其分为预后良好组、预后较差组、死亡组,分析预后与心肌酶的相关性;使用SPSS 19.0统计软件对数据进行处理。结果 3-5分组患儿心肌酶含量最高,6-8分组患儿次之,对照组最低,差异有统计学意义（P〈0.05）;预后良好组患儿心肌酶含量最低,预后较差组稍高,死亡组最高,差异有统计学意义（P〈0.05）。结论心肌酶含量与小儿重度感染性脑损伤的病情严重程度呈正相关,与预后呈负相关;医护人员可将心肌酶含量作为临床治疗及护理的参考依据。

英文摘要：

OBJECTIVE To investigate the correlation of severe infectious brain injury and myocardial enzyme profiles so as to provide evidence for clinical treatment and care.METHODS Totally 70 cases of pediatric patients with severe infectious brain injury in the hospital during May 2012 to Jun.2013 were selected as the research subjects and were divided into the group of 3-5points（n=37）and the group of 6- 8points（n=33）according to the Glasgow coma score（GCS）.Another 35 healthy children were selected as the control group.The cardiac enzyme levels of 105 cases of children were determined at the day of examination to analyze the correlation of brain damage and cardiac enzyme.According to the prognosis,the patients were divided into the good prognosis group,the poor prognosis group and the death group to analyze the correlation of prognosis and cardiac enzymes.The statistical soft SPSS19.0was used for data process.RESULTS：The cardiac enzyme level was the highest in the group of 3-5points,followed by the group of 6- 8points,the control group the lowest,with significance（P〈0.05）.The cardiac enzyme level was the lowest in children with good prognosis and slightly higher in the poor prognosis group,the highest in the death group,the difference was significant（P〈0.05）.CONCLUSION The results showed that the severity of the disease was positively correlated with cardiac enzyme levels and negatively correlated with the prognosis.Medical staff can take the myocardial enzyme level as a reference in future clinical treatment and care.