中文摘要：

目的 研究双酚A（BPA）对秀丽隐杆线虫寿命的影响.方法 采用固体培养方式评价0（对照组）、1、10、100、1000 μmol/L BPA对线虫寿命的影响（每组各70条）.结果 1、10、1000 μmo]/L BPA对线虫寿命无明显影响,与对照组比较,差异无统计学意义（P＞0.05）.与对照组比较,100 μmol/L BPA可延长线虫的寿命（P＜0.05）,最长生存时间由15d延长至17 d,中位生存时间由12d延长至13 d.结论 1、10、1000 μmol/L浓度下BPA不会缩短线虫寿命,100 μmol/L BPA可以延长线虫寿命.

英文摘要：

Objective To study the effect of bisphenol A （BPA） on the lifespan in Caenorhabditis elegans （C.elegans）.Methods Solid culture was used to evaluate the effect of 0 （control group）,1,10,100,1000 μ mo]/L BPA on the lifespan in C.elegans （with 70 in each group）.Results 1,10,1000 μ mol/L BPA had no significant effect on the lifespan of C.elegans,compared with control group,the differences were not statistically significant （P ＞ 0.05）.Compared with control group,100 μ mol/L BPA extended the lifespan of C.elegans （P ＜ 0.05）,the longest survival time from 15 d extended to 17 d,the median survival time from 12 d extended to 13 d.Conclusion 1,10,1000 μmol/L BPA do not shorten the lifespan in C.elegans,100 μmol/L BPA can extend the lifespan of C.elegans.