用磁过滤阴极真空弧源法在单晶硅基片上制备纯铁薄膜,分析了薄膜表面的组成、元素价态和薄膜的物相结构,研究了薄膜的腐蚀降解行为和抗凝血性能.结果表明:具有纳米晶粒的纯铁薄膜其腐蚀速率低于普通晶粒的纯铁,在纯铁薄膜表面粘附的血小板数量少于316L不锈钢,且激活和团聚比较轻微,增生的伪足数量比较少;纯铁薄膜表面对血浆中的凝血因子激活比较轻微,具有较好的抗腐蚀性和血液相容性.
Pure iron thin film was prepared on silicon substrate by filtered cathodic vacuum arc technique. The chemical composition of the film and the element valence state were investigated. The phase structure was examined, and the degradation behavior of the film was evaluated. In vitro blood compatibility tests, including platelets adherent, prothrombin time (PT) and thrombin time (TT), were adopted to evaluate the blood compatibility. The results show that the corrosion resistance of nanocrystalline pure iron film is superior to that of iron with coarse grain size. Platelets adhesion, aggregation and activation on the pure iron film are reduced compared to 316L stainless steel. The tests of PT and TT for iron thin films show that the activation of coagulation factors is very slight, showing that the pure iron film has good corrosion resistance and blood compatibility.