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中文摘要：
目的：初步查明某院围手术期抗生素相关性肠炎的疾病负担。方法：以使用了止泻药为线索，查阅手术科室相关病史，找出抗生素相关性肠炎，与对照组进行比较，统计不合理使用抗生素的发生率以及加重经济负担的量化指标。结果：从2007年1月-7月，共查阅相关科室4278个围手术期病例，发现抗生素相关性肠炎38例，其不合理使用抗生素的发生率为42．1％，显著高于对照组，并且使住院总费用共增加489022元。结论：腹泻前抗生素使用时间为抗生素相关性肠炎的诱发因素。围手术期抗生素相关性肠炎有较大的疾病负担，采取有效措施降低其发生率意义重大。
英文摘要：
OBJECTIVE To find out the disease burden of antibiotic associated colitis after surgery in the hospital. METHODS To search the disease cases in which antidiarrheal agents were used, found out antibiotic associated colitis, and calculated the incidence of irrational use of antibiotics and the number of the disease burden comparing with the contrast. RESULTS From 2007-01 to 2007-07,4 278 cases had been examined, and 38 antibiotic associated colitis had been found out, the hospitalization expenses increased 489 022 yuan. The incidence of the irrational use was 42. 1% which was higher than the contrast group. CONCLUSION The duration of using antibiotics before antibiotic associated colitis was the inducing factor. The disease burden was high, and the effective measure must he taken to decrease its incidence.
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