中文摘要：

以间苯二酚和氰基乙酸为主要原料，经Pechmann反应，水解，甲醚化，Williamson反应合成了7种新的4-甲氧基-7-乙氧基香豆素及其衍生物。考察了影响Williamson反应的因素，Williamson反应的优化条件为，DMF溶剂中，n（4-甲氧基-7-羟基香豆素）：n（卤代烃）：n（碳酸钾）：n（TEBA）=1：1.5：2.5：0.15，60℃反应25h，产率在57％～95％。中间产物及目标产物结构经IR，MS，^1H NMR表征得以证实。

英文摘要：

Seven new 4-methoxy-7-ethoxycoumarin and its derivatives were synthesized from resorcinol and cyanoacetic acid by Pechmann reaction, hydrolyzation, methyl etherization and Williamson reaction. The optimum conditions for Williamson reaction were determined. When n（4-methoxy-7-hydroxycoumarin） ： n （alkylhalides） ： n（anhydrous potassium carbonate） ： n（TEBA）=1： 1.5 ： 2.5 ： 0.15 and reacting at 60℃ for 25 h in DMF, the yields were between 57% - 95%. The structures of the intermediates and the products were confirmed by IR, MS and ^1H NMR.