重离子(C离子)用于肿瘤放射治疗具有物理学和生物学两方面的优势,被誉为面向21世纪最佳放疗用射线。综合论述了世界各国重离子束治癌的发展历史,在日本国立放射医学综合研究所(NIRS)提供的临床试验数据基础上分析了C离子束治疗的适应症以及对正常组织的放射损伤。此外,通过分析潜在患者人数和治疗相关硬件与软件设备,对C离子束治癌的运用前景做了初步评估。
Heavy ions (carbon ions) were considered currently as the best radiation in radiotherapy for their two superiorities in the physical and biological properties. This paper firstly put the focus on the history of development of heavy-ion radiotherapy in the world, then a comprehensive analysis of the indications and radiation damages of normal tissues in clinical trails of heavy-ion therapy was made based on the published data by NIRS. Moreover, the prospect of using carbon ions in radiotherapy was estimated by analyzing the potential patients' number, its related instruments and etc.