中文摘要：

叶酸是一种与肿瘤发生发展关系密切的人体必需微量元素。近年来研究发现叶酸缺乏或代谢障碍可能与胰腺癌的发生有关,其机制至今未明。本文从流行病学角度总结了叶酸与胰腺癌的关系,并就叶酸缺乏可能导致肿瘤的机制等方面对该领域的研究进展情况进行了综述。

英文摘要：

Folic acid,an essential microelement to human,is closely related to tumor development and progression.Recent studies have suggested that a low folate intake and impaired folate metabolism may be involved in the carcinogenesis of pancreatic cancer,but the specific mechanism remains unclear.In this paper we review the progress in the association of folate deficiency with pancreatic cancer from an epidemiological perspective,and introduce the progress in the mechanism by which folate deficiency causes tumor.