随着我国社会经济和城市化的快速发展,大气颗粒物是影响我国城市空气质量的首要污染物,大气细颗粒物污染已严重威胁我国居民健康。本文简要综述了PM2.5诱导的氧化应激和炎症反应在糖尿病的发生和发展中的分子作用机制。
An increasing number of epidemiological and experimental studies demonstrate the adverse effect of air pollution as one of major risk factors with consequences on human health in both industrialized and developing countries. Ambient fine particulate matter(PM2.5) is associated with a propensity to chronic diseases, including diabetes mellitus. The recent studies have provided a new link to PM2.5-induced oxidative stress, inflammation and insulin resistance. In this review, we focused on the PM2.5-induced oxidative stress and inflammation how these factors contribute to the progression and development of diabetes mellitus.